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September 7, 2012

wise words

A good leg will fall; a straight back will stoop; a
black beard will turn white; a curled pate will grow
bald; a fair face will wither; a full eye will wax
hollow: but a good heart, Kate, is the sun and the
moon; or, rather, the sun, and not the moon; for it
shines bright and never changes, but keeps his
course truly.

Ocoee River Playboat Race 2012

I love it.

September 6, 2012

My Guitar Hero



"The Descent" is the first single off of Bob Mould's new album Silver Age.  This is the best album I've bought in recent memory; the song "Keep Believing" is just. damn. awesome.   I lack proper superlatives this morning.  Just... get it.

Mind-Blowing

For those of you who took my recommendation and read The Emperor of All Maladies, you will really appreciate how mind-blowing this article is: http://www.nytimes.com/2012/09/06/science/far-from-junk-dna-dark-matter-proves-crucial-to-health.html?pagewanted=all
From the article:"The human genome is packed with at least four million gene switches that reside in bits of DNA that once were dismissed as “junk” but that turn out to play critical roles in controlling how cells, organs and other tissues behave. The discovery, considered a major medical and scientific breakthrough, has enormous implications for human health because many complex diseases appear to be caused by tiny changes in hundreds of gene switches."

And:

 "Human DNA is such a long strand — about 10 feet of DNA stuffed into a microscopic nucleus of a cell — that it fits only because it is tightly wound and coiled around itself. When they looked at the three-dimensional structure — the hairball — Encode researchers discovered that small segments of dark-matter DNA are often quite close to genes they control. In the past, when they analyzed only the uncoiled length of DNA, those controlling regions appeared to be far from the genes they affect."

This is an example of something I wish more engineers could get their paws on - 3d models of the way DNA is coiled into the nucleus of a cell...  

Thank you Government Sponsored Research btw.  

September 5, 2012

The music makes it wonderful



The big chroma-key eyeglasses and 1971 pant-suits etc. help make it wonderful too!